Zolmitriptan Tablets

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Zolmitriptan 2.5mg tablets are commonly prescribed for use in the treatment of migraine and cluster headache.

Zolmitriptan is a serotonin receptor agonist, belonging to a class of drugs known as the triptans. Zolmitriptan tablets work to treat the root cause of migraines through a complex neurological mechanism of action. By acting on serotonin (5HT) receptors, Zolmitriptan tablets enable the narrowing of blood vessels in the brain. This contricting effect is what results in the effective treatment of migraine and its associated symptoms.

Migraine is defined as a moderate to severe headache. Indicative signs of migraine are a throbbing pain on the side of the head often accompanied by other symptoms such as nausea and vomiting, as well as a heightened sensitivity to light and/or sound, referred to as aura. In certain individuals these associated symptoms can be experienced without a headache in what is called a silent migraine.

Patient information

*Always read the patient information leaflet before starting your treatment.

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Why choose Zolmitriptan tablets?

Effects of migraine can be wide ranging and debilitating, commonly interfering with a suffers ability to work, study, and complete day to day tasks. Over time, suffering from migraine attacks can also negatively impact your quality of life, putting strain on both professional and personal relationships.

Zolmitriptan tablets are a commonly prescribed, effective treatment for migraine. Zolmitriptan tablets have a fast onset of action, meaning they are able to alleviate symptoms of a migraine within 30 minutes.

Zolmitriptan tablets should be used to treat the symptoms of migraine only, and not used as a preventative measure for migraine associated symptoms.

What dose should I choose?

The recommended starting dose of Zolmitriptan tablets in accordance with the British National Formulary (BNF) is 2.5mg to be taken at the onset of a migraine attack, followed by 2.5mg at least 2 hours later if symptoms of migraine recurs. This can be increased to 5mg for subsequent attacks only in patients not achieving satisfactory relief with 2.5mg.
If symptoms persist for more than 2 hours and there is no response to the initial dose, a second dose should not be taken for the same attack. 

The maximum daily dose of Zolmitriptan tablets is 10mg in any 24-hour period. Zolmitriptan is licensed for use in adults between the ages of 18-65 years.

For more information on which combination to choose or to find out if Zolmitriptan tablets are right for you, speak to one our expert pharmacists on 0203 167 8789.

Buy Zolmitriptan tablets online in the UK for the effective treatment of migraine at Smart Chemist.

How should I take Zolmitriptan tablets?

Zolmitriptan tablets should be taken orally at the onset of a migraine attack, and swallowed whole with a glass of water. Zolmitriptan tablets can be used alongside other forms of analgesia such as paracetamol and ibuprofen.

How do Zolmitriptan tablets work?

Migraine symptoms have been linked to the temporary widening of blood vessels in the brain, resulting in the throbbing like pain commonly associated with migraine. Zolmitriptan is a selective serotonin (5HT) receptor agonist. It works to treat migraine symptoms by specifically acting on serotonin receptors in the brain, stimulation of which results in the narrowing of blood vessels returning them back to their original state.  

Zolmitriptan tablets should be used to treat the symptoms of migraine only, and not used as a preventative measure.

What are the side effects of Zolmitriptan?

Side effects commonly associated with Zolmitriptan tablets include:

  • Abdominal pain
  • Drowsiness
  • Dry mouth
  • Muscle weakness
  • Palpitations


To find out more about the associated side effects of Zolmitriptan tablets please read the patient information leaflet provided or contact your doctor. Alternatively, you can speak to one of our expert Pharmacists at Smart Chemist.